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Challenges

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Rules Card Icon.png For corresponding page on Binding of Isaac: Rebirth Wiki, see Challenges.

Challenges are unique runs in the game. Challenges typically start the player off with one or more specific items which make normal play more difficult.

Scissors Icon.png The Modding of Isaac Scissors Icon.png

MainPageModdedBosses.png Bosses MainPageChallenges.png Challenges MainPageModdedChapters.png Chapters MainPageModdedCharacters.png Characters Questionmarkisaac.png Curses/Blessings MainPageModdedItems.png Items Dataminer Icon.png Mods
Baby Transformation.png Modders/Teams MainPageModdedMonsters.png Monsters MainPageModdedObjects.png Objects MainPageModdedPickups.png Pickups MainPageModdedRooms.png Rooms MainPageModdedTransformations.png Transformations MainPageModdedTrinkets.png Trinkets